Specifically, our expert teams around Prof. Dr. Justo Lorenzo-Bermejo (Institute of Medical Biometry and Informatics, Heidelberg) and Dr. Dr. Daniel Hübschmann (Dr. Nagarajan Paramasivam; Computational Oncology (CO), Molecular Precision Oncology, NCT, Heidelberg) combine and evaluate the multiple data types collected in complex biostatistical and integrative data analyses. A further expert team led by Prof. Dr. Jan Korbel (EMBL) concentrates on the causes and consequences of germline and somatic genetic variation and their association with disease, with particular emphasis on genomic structural variation.